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Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV.

Identifieur interne : 000698 ( 2020/Analysis ); précédent : 000697; suivant : 000699

Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV.

Auteurs : Juanjuan Zhao [République populaire de Chine] ; Xuejiao Liao [République populaire de Chine] ; Haiyan Wang [République populaire de Chine] ; Lanlan Wei [République populaire de Chine] ; Mingzhao Xing [République populaire de Chine] ; Lei Liu [République populaire de Chine] ; Zheng Zhang [République populaire de Chine]

Source :

RBID : pubmed:32270178

Abstract

The effect of host immune status on SARS-CoV-2 infection remains unknown. Here, we report the first case of COVID-19 with HIV-1 and HCV co-infection, who showed a persistently negative SARS-CoV-2 RNA test, but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on the early SARS-CoV-2 clearance.

DOI: 10.1093/cid/ciaa408
PubMed: 32270178


Affiliations:


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pubmed:32270178

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